Free Standard Shipping on ALL PremiershopMD Orders!

Obagi Tretinoin 0.025% Cream

Acne treatment cream
Topical treatment for acne vulgaris. Available by prescription only, all Obagi tretinoin formulations are non-comedogenic and fragrance free.

Prescription required. Contact your healthcare provider to purchase, or find a nearby physician who offers this product.
Call for Price
Earn 105 Premier Points
Tretinoin is the generic name for synthetic, first-generation all-trans-retinoic acid. Topical tretinoin first arrived on the dermatology scene in the 1960s. It is a prescription drug approved to treat acne, and in a few other FDA-approved products, to treat fine facial wrinkling, limited psoriasis, and other conditions.

Available in multiple strengths and formulations by prescription only, Obagi tretinoin creams and gel work deep inside the skin to treat acne.
Each gram contains:
Tretinoin 0.025%, stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, and purified water

Chessney Miller

9 days ago

Great product! I use a small amount mixed with Obagi moisturizer at night and my skin has never felt or looked better!

Rhonda Vanover

1 months ago

Amazing

Deanna Sholas

1 months ago

After purchasing I noticed this product is also avaliable in 0.05% as a gel. I will try next because I already like this one.

Megan Morrow

2 months ago

I love this product!! 10/10 recommend!

Casey Zier

2 months ago

Worth every penny

Danielle Capogna

2 months ago

Perfect for my daughter

Josey Whorley

2 months ago

so good!

Mariah Vasquez

3 months ago

great to start and work up to a stronger tret

Melissa Thompkins

4 months ago

Amazing

Nicole Sisk

5 months ago

A necessary product for keeping your skin smooth and useful.

Morgan Butler

6 months ago

Has really helped improve fine lines

Cheryl Blair

6 months ago

Love with the blender

Heather Goodenow

8 months ago

Mu absolute favorite product!!

Donna Caudle

8 months ago

This is the absolute best stuff ever!! Cleared my adult acne and helping shrink my pores and control oil

Britnee Palshan

8 months ago

❤️❤️❤️

Patricia Campola

9 months ago

Excellent product!! My skin looks amazing.

Rima Hammoud

9 months ago

Great product

Carrie Coleman

10 months ago

Works great!!! My skin has really started looking better.

Karla Mancilla

10 months ago

Gentle but soooo effective!!!

Gloria Buccino

1 years ago

Thumbs up for this cream, would purchase again

Dawn Olinger

1 years ago

A little bumpy to start as it brings all blemishes to the surface but give it a couple weeks and skin is blemish free

Ashley Reeves

1 years ago

I think this product is affective. It feels like a hydrocortisone cream and takes a second to fully rub into the skin. I can feel it on my skin but it doesn’t feel greasy. I am excited to see how it works after six months.

Megan Culbreth

1 years ago

Obagi Tretinoin is a must have product!

Need to Know

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: or Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: or Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

Precautions: Exposure to sunlight, including sunlamps, should be minimized during the use of Tretinoin Cream and Gel, and patients with sunburn should be advised not to use the product until fully recovered.

Patients who have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution. Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided.

Weather extremes, such as wind or cold, also may be irritating to patients using tretinoin.

Tretinoin Cream and Gel should be kept away from the eyes, the mouth, angles of the nose, and mucous membranes. Topical use may induce severe local erythema and peeling at the site of application. If the degree of local irritation warrants, patients should be directed to use the medication less frequently, discontinue use temporarily, or discontinue use altogether.

Tretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition.

Pregnancy Tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Adverse Reactions The skin of certain sensitive individuals may become excessively red, edematous, blistered, or crusted. If these effects occur, treatment should be discontinued or adjusted to a level the patient can tolerate.

To report SUSPECTED ADVERSE REACTIONS contact FDA at fda.gov/medwatch or call 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: or Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

How to Use

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication onto fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin, and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes, and open wounds
  • Tretinoin is for topical use, only.
  • Tretinoin should be applied once daily, or as directed by physician.
  • Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription.
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes.
  • Application of excessive amounts of gel will not provide incremental efficacy.
  • Store tretinoin cream at controlled room temperature below 80°F

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication onto fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin, and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes, and open wounds
  • Tretinoin is for topical use, only.
  • Tretinoin should be applied once daily, or as directed by physician.
  • Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription.
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes.
  • Application of excessive amounts of gel will not provide incremental efficacy.
  • Store tretinoin cream at controlled room temperature below 80°F