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Obagi Tretinoin 0.05% Cream

Acne treatment cream
Topical treatment for acne vulgaris. Available by prescription only, all Obagi tretinoin formulations are non-comedogenic and fragrance free.

Prescription required. Contact your healthcare provider to purchase, or find a nearby physician who offers this product.
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Tretinoin is the generic name for synthetic, first-generation all-trans-retinoic acid. Topical tretinoin first arrived on the dermatology scene in the 1960s. It is a prescription drug approved to treat acne, and in a few other FDA-approved products, to treat fine facial wrinkling, limited psoriasis, and other conditions.

Available in multiple strengths and formulations by prescription only, Obagi tretinoin creams and gel work deep inside the skin to treat acne.
Each gram contains:
Tretinoin 0.05%, stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, and purified water

Zarah Celino

5 days ago

Great product

Karen Anderson

6 days ago

F do hgg

Courtney Wolbert

14 days ago

Good product

Christine Pelic

22 days ago

Wotks great for fine lines and wrinkles. My skin looks clearer and brighter with regular use. Make sure to dry face and gradually work toward using every night to avoid peeling.

Jessica Staiger

1 months ago

I live for this! Helps with breakouts

Megan Swanson

1 months ago

Noticeable difference in my complexion and texture on my face and neck within a couple of weeks. I eased into the treatment and didn't have any skin sensitivities. In love!

Elizabeth Serrano

1 months ago

This product has been life changing! Works well as a spot treatment and a daily application

Sara Adams

1 months ago

More even skin tone noted

Luisa Salazar

1 months ago

Great for my stubborn blemishes and has helped with fine lines too.

Allison Zarzosa

1 months ago

Great!

Jessica Peine

1 months ago

I used this starting in March 2021, after having used Epiduo for nearly 2 years. I researched how to deal with skin adjusting to tretinoin so I could be prepared for initial side effects, and I was fine within a month. My acne has reduced even more, and my face does have a nice glow. Great product!

Monica Correll

1 months ago

I highly recommend tretinoin cream. It undoubtedly keeps my skin youthful looking.

Crystal Primm

2 months ago

I wish i could rate this 100 stars!

Merydith Vann

2 months ago

I feel like it brighting of my skin and works well with exfoliation.

Katherine LaHurd

2 months ago

This has evened out my skin tone so much!

LINDSEY MEARS

3 months ago

A staple for skincare!

Brenda Kohls Medlock

3 months ago

This little tube along with the blender is the perfect pairing against wrinkles. I get compliments on my skin often. At the age of 62...I will take them!

Princess Tucker

3 months ago

I started using this product over 6 months ago, it works wanders. . Have deen a big inprovement in my skin tone . The product is expensive but its worth it. Very pleased

Alicia Tomkin

4 months ago

So far so good. Ive been using this for about 2 months and liking the entire system a lot.

Reanee Grab

4 months ago

Worked well, but should of started with a stronger dose.

Adriane Ayerdis

4 months ago

Good for first starting off but did switch to higher percentage.

Taylor Dettman

4 months ago

This product has been a game changer for my skin! Love!!

Patty Cooper

4 months ago

Just 4 weeks in and minimal reactions. Quality product.

Bethene Newland

5 months ago

Great product

Victoria Ramon

5 months ago

wonderful!

Haley White

5 months ago

The best

Mylene Santos

6 months ago

Love it

Kristen Jurado

6 months ago

Great intro level, not too irritating. I was even able to ise on my neck and chest.

Megan Wieder

6 months ago

makes my skin texture so smooth!

Amanda Mahoney

6 months ago

Great product! Just the right strenght and does not dry out my skin. My wrinkles have noticably decreased!

Laura Mahoney

6 months ago

My brown spots are fading fast.

Ivana Markovic

7 months ago

Really works!!

Sally Taylor

7 months ago

This wAs my first tretinoin cream with my first obagi kit . Iove them all

Julianne Parker

8 months ago

Love it

Cathy Obrien

8 months ago

This makes a huge difference!

Ana Vega

8 months ago

Smooth application - potent

Jennifer Toccaceli

8 months ago

Best retinoin ever used!

Myra Crowe

9 months ago

Na

Tiffany Keller

9 months ago

Amazing product.

Christi Rodriguez

9 months ago

Great product!

Abby Potts

10 months ago

This has changed my skin. So happy with results!

Christine Albert

10 months ago

Great. No fragrance. Great for sensitive skin

Catherine Miele

10 months ago

I also use the blender with this product. I spread it to my overall face and have seen how my skin is being exfoliated slowly. My skin has a new fresh appearance.

Ilyssa Feierstein

11 months ago

Another great product!

Mary Meek

11 months ago

This retinol cream is unlike any other! I use it every other night and as a spot treatment for any acne that comes up!

Michaela Campbell

11 months ago

This Obagi product is MUST

Raquel Balan

1 years ago

Top rated

Harleigh Peluso

1 years ago

Love it

Shelley Kluz

1 years ago

Love it!!

Rima Hammoud

1 years ago

Wow this stuff is amazing.

Nicole Strohl

1 years ago

Works great!

Beth Stewart

1 years ago

Works great

Jaclyn Zatezalo

1 years ago

Have tried the gel also, but this one free bit more hydrating. Wake up every morning with glowing skin

Satanya Clarke

1 years ago

The best

Stephanie Logan

1 years ago

A little bit goes a long way. Real the instructions and speak with your Doc. Tube usually lasts 6+months, currently pregnant and no longer using. Hopefully the product stays good :-/

Renee Kim

1 years ago

its great

Elizabeth Watkins

1 years ago

Love this product! It has cleared up my face and smoothed out my skin texture.

Amy Hansen

1 years ago

Works great and doesn’t irritate my skin.

Suvd Baljinnyam

1 years ago

Great product!

Heidi Ryan

1 years ago

Miracle worker!! Fine lines are vanishing every day. I highly recommend this to everyone who wants their youth restored. Make sure to take a before picture so you can watch the results.

Megan Culbreth

1 years ago

Love this Tretinoin! Perfect for more oily prone skin!

Nichole Grazioli

1 years ago

Love this. I can definitely feel it working. I enjoy the lower percent option and the ability to work my way to the next level.

Trish Walstead

1 years ago

A must add on to your routine!

Tina Tinoco

1 years ago

This is a must to move up the Tretinoin %. You can’t just start on the .10, you need to work your way up slowly before using the strongest % which in my opinion is the best way to go.

Melinda Visser

1 years ago

Tretinoin is my favorite product. It gives me amazing results!

Savannah HUTTO

1 years ago

Too irritating for me, despite gradual incorporation.

Tammy Collins

1 years ago

Great product! I am not disappointed

Need to Know

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

Precautions: Exposure to sunlight, including sunlamps, should be minimized during the use of Tretinoin Cream and Gel, and patients with sunburn should be advised not to use the product until fully recovered.

Patients who have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution. Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided.

Weather extremes, such as wind or cold, also may be irritating to patients using tretinoin.

Tretinoin Cream should be kept away from the eyes, the mouth, angles of the nose, and mucous membranes. Topical use may induce severe local erythema and peeling at the site of application. If the degree of local irritation warrants, patients should be directed to use the medication less frequently, discontinue use temporarily, or discontinue use altogether.

Tretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition.

Pregnancy: Tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Adverse Reactions: The skin of certain sensitive individuals may become excessively red, edematous, blistered, or crusted. If these effects occur, treatment should be discontinued or adjusted to a level the patient can tolerate.

To report SUSPECTED ADVERSE REACTIONS contact FDA at fda.gov/medwatch or call 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

How to Use

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication on to fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes and open wounds
  • Tretinoin is for topical use, only. 
  • Tretinoin should be applied once daily, or as directed by physician.
  • Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription.
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes. 
  • Application of excessive amounts of gel will not provide incremental efficacy.
  • Store tretinoin cream at controlled room temperature below 80°F

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication on to fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes and open wounds
  • Tretinoin is for topical use, only. 
  • Tretinoin should be applied once daily, or as directed by physician.
  • Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription.
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes. 
  • Application of excessive amounts of gel will not provide incremental efficacy.
  • Store tretinoin cream at controlled room temperature below 80°F